The actual reason behind not chewing the Tulsi leaves is due to its mercuric content. German researchers have discovered that the leaves of the holy Tulsi plant contains traces of mercury. If the leaves are chewed, the mercury may damage the teeth. But when taken as a whole, the mercury is found beneficial for the digestive system.This mercury content is now being used in anti-cancer drugs.Thus, by weaving a legend around the Tulsi plant, the ancient Vedic Indians accomplished 2 things: firstly, the Tulsi plant would be worshipped in all homes, and thus its medicinal properties would be effectively utilised. Secondly, by calling it Lord vishnu's wife, it could not be chewed, thus preventing damage to our teeth.
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